PRECIOUS: pharmacology lecture this morning [yesterday] on autonomic nervous system drugs, mechanisms, etc, given by Dr. T. C. Theoharides, Ph.D., M.D. Professor of Pharmacology, Internal Medicine and Biochemistry; Associate Professor of Psychiatry; Director, Molecular Immunopharmacology and Drug Discovery Laboratory- Department of Pharmacology and Experimental Therapeutics at Tufts University School of Medicine. Clinical Pharmacologist, Massachusetts, Director Drug Formulary Commission (appointment 1986-2010).

we're going over treatments for depression and he's talking talking talking about the mechanisms of all the MAOIs, SSRIs, tricyclics, etc, and I'm writing writing writing all these notes and trying to catch everything he's saying about how such and such neurotransmitter is the target of this drug, and such and such other neurotransmitter is the target of this other drug, etc etc...

and then he says, after like, the entire hour lecture -- "so what's the main point of all of this information? the point is that we have absolutely no idea how to treat depression."

i thought you'd appreciate that.